It has been found that certain platinum containing compounds act as anticancer drugs or as agents to cleave proteins.  In order to find new compounds that can be able to perform the functions of known platinum compounds, molecular mechanics calculations are performed.  This modeling helps us pinpoint compounds in order to conserve time and resources that would be spent doing laboratory studies as well as acting as a confirmation for data found in the laboratory.  For our modeling we used a modified AMBER force field and tested how our platinum compounds would interact with proteins and DNA.  Previous molecular mechanics analysis of Pt(Me<sub>4</sub>en)(methionine)<sub>2</sub> complexes [Me<sub>4</sub>en = N,N,N',N'-tetramethylethylenediamine] revealed significant steric clashes; experimental studies confirmed that such a complex did not form [Williams et al. <i>Inorganic Chemistry</i>, <b>2004</b>, <i>43</i>, 1190-1196].  Current studies are focused on platinum complexes with the diamine ligand N,N-diethylethylenediamine (Et<sub>2</sub>en) and either methionine amino acids or guanine nucleotides.  Significant differences between complexes with the Me<sub>4</sub>en and Et<sub>2</sub>en ligands are noted; the latter ligand has one nitrogen with relatively little bulk, and therefore the steric clashes are lessened in certain conformations of the Pt(Et<sub>2</sub>en)(methionine)<sub>2</sub> complex. Platinum complexes with other diamine ligands will also be considered.